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D1 S3:Recombinant Peptide Production and Host Cell Impurities Format: Presentations and a Panel Discussion with Q&A (Virtual and In-Person Attendees) This session examines best practices for controlling host cell impurities in recombinant peptide production, drawing on regulatory expectations and experience from 505(b)(2) applications and biologics (including insulins)
The peptide reduces production of pro-inflammatory cytokines including IL-1, TNF-, and IL-6 while enhancing expression of anti-inflammatory mediators such as IL-10 and TGF-, creating a cytokine milieu that supports tissue repair rather than ongoing damage
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