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Metabolic secondary outcomes included HbA1c, blood pressure (systolic and diastolic), HR, total cholesterol, triglycerides, hsCRP, HbA1c in participants with pre-existing pre-diabetes and T2D, blood pressure in participants with pre-existing hypertension and changes in T2D, and hypertension medication used in participants with T2D and hypertension, respectively
It belongs to a class of compounds known as metallopeptides, so its research relevance is directly tied to its ability to bind and transport copper at the cellular level
By contrast, exenatide and roflumilast were associated with greater uncertainty, with 95% credible intervals crossing the null