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doi: 10.1016/j.cell.2018.10.001 124 NakayaMXiaoYZhouXChangJ-HChangMChengXet al
Genistein inhibited eosinophil leukotriene (LTC)-4 synthesis from human peripheral blood eosinophil and inhibited phosphorylation of p38 mitogenactivated protein kinase (MAPK) and its downstream target MAPKAP-2, which in turn reduced the translocation of 5-lipoxygenase to the nuclear membrane
It is one of the most unique peptides in existence because it operates systemically
The upregulation of xCT induces oxidative stress resistance and protects against lipid peroxidation [90]
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