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LPS-mediated NFB activation and pro-inflammatory cytokine production decreased in neutrophil NFB led to a weakened inflammatory response in the acute phase of mice with acute lung injury, suggesting that H 2 O 2 can inhibit the acute excessive inflammatory response ( 2.2 GPX2 Glutathione peroxidase 2 (GPX2) is mainly expressed in the gastrointestinal system, including the intestinal epithelium, esophageal epithelial cells, etc., and can also be detected in the human liver ( 2 O 2 uptake is difficult to make the main function of GPX2

When cells are exposed to oxidative stress, Nrf2 is activated and translocates from the cytoplasm to the nucleus, where it binds to the antioxidant response element (ARE), triggering the expression of a series of antioxidant enzyme genes

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