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Sodium-glucose transporters (SGLT)-inhibitors The treatment of T2DM with glyflozines, sodium-glucose co-transporter 2 inhibitors, represents a new therapeutic approach ( Among SGLT2 inhibitors, three of them have been approved by the FDA and EMA: canagliflozin (2013), dapagliflozin (2014) and empagliflozin (2014)
However, individual results vary significantly, and semaglutide has stronger cardiovascular outcomes data
Post hoc Tukey HSD analysis indicated that TNF- concentrations were significantly higher in the group STZ compared to the group STZR (p = 0.030), whereas no statistically significant difference was detected between the groups STZ and C (p = 0.062) or between the groups STZ and R (p = 0.089) (Figure 6B)
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