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Before diving into GLP-1 versus GIP specifically, understanding incretin hormones as a category provides helpful context
What the Trials Showed Tirzepatides efficacy is established across two landmark NEJM trials: SURMOUNT-1 (obesity) and SURPASS-2 (a head-to-head against semaglutide in type 2 diabetes)
And factors like stress, sleep disruption, and medication interactions can all blunt the appetite-suppressing effect temporarily
Ghasemi, R., Haeri, A., Dargahi, L., Mohamed, Z
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