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GPX was measured adding cell extract to 50 mmol/l potassium phosphate pH 7.0 containing 1 mM EDTA, 1.5 mM sodium azide, 0.15 IU of purified glutathione reductase from bakers' yeast, 0.45 mM GSH, 0.2 mM NADPH, 1.2 mM cumene hydroperoxide One unit of GPX was defined as the amount of enzyme which produces 1 mol of GSSG (oxidized glutathione)/min at 25C

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Cox M, Klutke JJ and Klutke CG: Assessment of patient outcomes following submucosal injection of triamcinolone for treatment of hunner's ulcer subtype interstitial cystitis

The mechanism likely relates to changes in appetite regulation and energy metabolism