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GLP-1 is an incretin hormone that is secreted in response to food intake, and it exerts multiple actions conducive to glycemic control, including enhancing glucose-dependent insulin secretion, suppressing glucagon release, and delaying gastric emptying [39]
Lactate is formed, reductively, from pyruvate as the final reaction of glycolysis, diverting pyruvate from oxidation to acetyl-CoA which is the first step in oxidative phosphorylation
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