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All subjects were observed and assessed for side effects such as changes in alertness and general activity, the presence of excessive salivation, gagging, and regurgitation following each injection until the end of the experimental day (4 pm)

It increases melanin production in the skin by activating melanocortin receptors, leading to darker pigmentation

2026 - evaluation framing) New and diffuse pigmentation with systemic symptoms like fatigue, weight changes, or skin darkening elsewhere on the body - This pattern raises the possibility of an endocrine condition such as Addison's disease

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