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This synergy not only bolsters the drugs effectiveness but also holds the potential to reduce their gastrointestinal side effects, fostering a more tolerable and safer treatment experience

It also implies that a user can take their dose at any time of day, regardless of their desired health outcome

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-endorphin, the POMC-derived opioid peptide, has the capacity to upregulate melanogenesis and melanin distribution by promoting maturation of melanocytes and arborisation of their dendritic processes, thus increasing the efficacy of the transfer and distribution of melanosomes to neighbouring keratinocytes [23, 29]