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PI3K/Akt/mTOR + MAPK/ERK Activates both the metabolic (PI3K/Akt/mTOR - protein synthesis, glucose uptake) and proliferative (MAPK/ERK) IGF-1 signalling cascades

While Ozempic works to suppress hunger and assist in weight management, cannabis use might counteract these benefits by boosting appetite

A landmark study published in PNAS demonstrated that Akkermansia muciniphila interacts directly with the intestinal epithelium and that, in animal models, administering this bacterium reversed key markers of diet-induced obesity, including fat mass gain, metabolic inflammation, and gut barrier disruption