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Systemic depletion of l-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
(4) Focusing on the specific alterations, the C-terminus of Tesamorelin is modified by the addition of a trans-3-hexenoic acid group
Pharmacological activation or genetic restoration of this axis, using agents such as DCA to inhibit pyruvate dehydrogenase kinase, reactivated mitochondrial oxidative phosphorylation, increased reactive oxygen species production, and triggered apoptosis in cancer cells
Importantly, a non-destructive signal amplification tactic for GSH monitoring in living cells was developed
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