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Legal status (US): Sermorelin has a documented, two-part FDA approval history under the brand name Geref, both approvals held by Serono (later EMD Serono)
Desensitization and Diminished Effects IGF-1 receptor downregulation can occur with chronic use, diminishing results over time and increasing the need for cycling or periodization
The small number of studied patients in each group may be behind the non significant correlation
It is not uncommon to see BPC 157 mentioned in forums and weight-gain testimonials
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