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This reaction has two consequences studied in the literature: it consumes S-adenosyl methionine, the cells principal methyl donor, and it removes nicotinamide from the salvage pathway that regenerates NAD+
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Drowsiness, weakness Nerve injury accompanied by tingling and numbness in the hands and legs Loss of memory, confusion Dementia Depression Seizures Recommended Amounts of Vitamin B12 For men and women 14 years of age and older, the Recommended Dietary Allowance (RDA) is 2.4 micrograms (mcg) per day
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