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Theyve been overwhelmed by demand for a thinner type of needle often used to inject heroin or methamphetamines
The review process under Health Canadas standard pathway takes approximately twelve months, though priority review can reduce this to six to eight months for medications addressing significant unmet needs
However, in this trial, weight loss response to semaglutide 2.4 mg at 68 weeks was not related to meal-stimulated endogenous GLP-1 response at baseline, suggesting that the supraphysiological effect of semaglutide probably overrides the biological mechanisms linked to a suboptimal clinical response
doi: 10.1192/j.eurpsy.2025.10125 Summary Keywords dopamine, GABA, ghrelin, GLP-1 RA, inflammation, leptin, suicidality Citation Borovcanin MM and Petrovic I (2026) Suicidality as a potential risk and therapeutic target during widespread GLP-1 receptor agonists use: implications of inflammation
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