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In a group of patients who had antibodies to tesamorelin after 26 weeks of treatment (56%) and were re-assessed 6 months later, after stopping tesamorelin treatment, 18% were still antibody positive

Although substantial evidence suggests that an increase in the level of TMAO is associated with the risk of cardiovascular diseases including atherosclerosis, chronic kidney disease, and hypertension, the direct effect of TMAO on vascular endothelial function remains unclear

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