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Over the past few years, incretins have been clinically validated as targets and are now the emerging standard of care therapies in obesity, but could also be effective in other metabolic indications, as well as in cardiovascular and chronic kidney disease
Two of the most talked-about metabolic peptides in current research circles are retatrutide and MOTS-c
Figure 1 shows a phylogram based on the aminoacid sequences of the 18 distinct gene products occurring as soluble dimeric proteins in humans
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