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1, 2 IGF-1R is primarily activated by its high-affinity ligands, IGF-1 and IGF-2, though it can also bind insulin with lower affinity
C., Chiu, K., & Lee, C
The SUSTAIN-6 trial demonstrated that Ozempic significantly reduces the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes and established cardiovascular disease
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