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Amides Specification Reference Organic Chemistry, Nitrogen compounds 34.3 Quick Notes Amide formation : Ammonia + acyl chloride forms a primary amide Primary amine + acyl chloride forms a secondary amide Reactions of amides : Hydrolysis : Acid hydrolysis gives a carboxylic acid Alkali hydrolysis gives a carboxylate salt Reduction with LiAlH forms an amine 4 Basicity : Amides are much weaker bases than amines because their nitrogen lone pair is delocalised into the carbonyl group, reducing its ability to accept protons

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