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In: Ennen G, Kuiper HA, Valentin A, eds
A 2025 analysis by the Employers Health Coalition found that 64% of large employers (5,000+ employees) excluded GLP-1 medications for obesity from their health plans, citing projected costs of $12,000 to $15,000 per patient per year (Jain et al., Health Affairs 2025)
GLP-1-RA such as Ex-4 and Liraglutide modulate multiple signaling pathways in hMSC and progenitor cells to enhance osteogenesis, suppress adipogenesis, promote survival, and reduce inflammation
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