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However, the bioequivalence criterion for the AUC was met for ethinylestradiol in all cases, and the AUC for the progestin component was either unaffected or showed approximately 20% higher mean exposure, which is not considered to affect the safety or efficacy of the combined pills
Mean weight reductions were greater with all cagrilintide doses (roughly 6.0% to 10.8%) than with placebo (3.0%), and the top 4.5 mg dose modestly out-performed the active comparator, once-daily liraglutide 3.0 mg (10.8% vs 9.0%)
Exenetide is the oldest of the GLP-1 agonists approved to treat type 2 diabetes
