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Again, the copper uglies are rare, but its something to be cautious about
It activates metabotropic glutamate receptors (mGlu2), contributing to its long-term analgesic effects (Chiechio et al., 2007)
Whilst we found that ex vivo vehicle treated cells produced high levels of cytokines, including IL-5, IL-13, IL-9 ( Supplementary Figures 4BD ), and modest amounts of IL-10 and IL-6 ( Supplementary Figures 4E, F ), melatonin treatment greatly reduced the concentration of all cytokines analyzed ( Supplementary Figures 4B F )
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