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Description

( D ) Luminescent images of GLP1R/pCRE-luciferase/CHO-K1 cells treated with 01 M of exendin-4 or semaglutide with or without antagonist, exendin9-39 (500 nM)

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Heme induces ubiquitination and degradation of the transcription factor Bach1

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Receptor-specific differences include D9R7.35b and D15R299 salt bridges shared by GLP-1R and GIPR (but absent in GCGR, which has Q374 in ECL3 and I194 at position 2.67b), and GCGR-specific -stacking between Phe6 and Y138 1.36b

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