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In addition to these widely used AOMs, Exenatide, one of the earliest GLP-1 RAs approved by the FDA and EMA for T2DM management, is not indicated for weight management but remains clinically relevant, particularly in older adults with comorbid obesity and T2DM, given its long-term clinical experience and established tolerability profile [26,27,28]
Small peptides like bremelanotide hold out hope for cycle-linked symptoms like low libido and mood dips
Patients also risk needing future surgeries to address additional loose skin or tissue
Pharmacotherapy of type 2 diabetes: an update
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