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Deryabin Pavel et al., 2022
In the mouse model of STZ-induced DKD, proximal tubule-specific knockout of Atg5 aggravates tubule injury and kidney damage, reflected as defective autophagy sensitized proximal TECs to ferroptosis (79)
Long-chain acyl-CoA then binds to free carnitine in the mitochondrial outer membrane under the catalysis of carnitine palmitoyl transferase 1 (CPT1) to form LCACs
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