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Barrier methods, like condoms, are advised for 4 weeks after starting or increasing the dose, or a non-oral birth control could be used, such as the IUD, vaginal ring, or hormonal implant (6)

The review comprehensively explores the literature for evidence of the role of oxidative stress in conditions such as abortions, preeclampsia, hydatidiform mole, fetal embryopathies, preterm labour and preeclampsia and gestational diabetes

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Thus, the current literature does not support the concern of an increased risk of DKA in real-life practice, beyond levels seen in clinical trials