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The efficacy and safety of iGlarLixi was assessed in patients 65 versus 65 years of age) differed according to the absence or presence of comorbidities

Orforglipron also reportedly has a simpler production process than injected GLP-1 drugs such as Ozempic and tirzepatide (sold as Mounjaro) and does not require cold storage factors that could help improve access to the drug if it is approved for use

Restarting the medication helped restore some protection, but only partially, showing that discontinuation leaves a lasting scar. Healio previously reported that the discontinuation of GLP-1 receptor agonists was tied to weight regain and higher risks for some adverse pregnancy outcomes like gestational diabetes and preterm delivery

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