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125 A genome scan revealed that genetic variations in apelin (rs3761581/rs2235312/rs3115757) and its receptor APLNR (rs11544374/rs2282623) were significantly associated with HAPE
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As older molecules will lose patent over next years and a plethora of new molecules will come to the market, it is likely that competition will have a positive impact on the obesity medication prices [14]
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