mechanisms discussed in the article include copper binding, extracellular matrix signaling, fibroblast activity, collagen-related pathways, matrix metalloproteinase regulation, glycosaminoglycan synthesis, and inflammation-related pathways
Nature 380:435439 Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS et al (2003) The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis
To determine if GSH precursors accumulate and are possibly rerouted upon halting GSH synthesis in vivo, we performed targeted metabolite analysis on tissues from Gclc WT and KO mice
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