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From Uox knockout mice that establish a human-like uricase-deficient metabolic background, to huXDH and huURAT1 models that support target-specific pharmacology, and huNLRP3/huIL1B models that enable inflammatory pathway evaluation, Cyagens model portfolio is designed to support multiple stages of preclinical research
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This chronic inflammation, driven by excessive NO signaling, may lead to tissue damage and further facilitate polyp progression, positioning these proteins as promising biomarkers for diagnosis
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