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L-cells are nutrient sensitive and GLP-1 is secreted in response to glucose ( Reference Reimann, Habib and Tolhurst 21 ) , proteins ( Reference Hall, Millward and Long 22 , Reference Power, Conway and McCormack 23 ) peptides ( Reference Hira, Mochida and Miyashita 24 ) , amino acids ( Reference Oya, Kitaguchi and Pais 25 , Reference Reimann, Williams and Silva Xavier 26 ) and lipids ( Reference Lindgren, Carr and Deacon 27 )
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In cyanobacteria, sulfoxide synthase activity involved in EGT biosynthesis may be provided by OvoA, an enzyme involved in the biosynthesis of ovothiol A, another thiol-containing L-histidine derivative (Liao and Seebeck 2017)
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