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Additionally, they play a critical role in the metabolism of fats into glucose, which is fundamental for the function of aerobic cells to generate energy (11, 43)

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Patients with overweight, obesity, or metabolic syndrome risk factors such as hyperglycemia and dyslipidemia, should be screened for NAFLD by starting with a liver enzyme panel If NAFLD is present, sustainable lifestyle modifications including therapeutic dietary and exercise interventions should be implemented with regular follow up assessments Adding nutritional bioactives, such as glutathione, should be considered American Liver Foundation

One peptide contains a hydrophobic sequence at its N-terminus (PFVYLI-CAND) 44 , while the other includes a positively charged, hydrophilic HIV-TAT sequence at its N-terminus (CPP-CAND) 45 (Figure