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Clinical Importance: Bleeding time provides an estimate of platelet activity and capillary integrity, but it has largely been replaced by more accurate platelet function tests (e.g., platelet aggregation studies, PFA-100 test) in modern laboratories

Third, rapid weight loss itself depletes nutrients

In the absence of robust, high-quality evidence, clinical decisions should be guided by individual risk assessment and shared decision-making

The change of aldosterone concentration was significantly larger after liraglutide than after placebo only in patients with eGFR 60 ml/min/1.73 m 2 , ( 7.3) [95%CI ( 11.7)( 0.2)] and ( 0.3) [95%CI ( 2.2)(3.8)] respectively, ( p = 0.007)