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10.1016/j.bbabio.2017.04.002 Biochim
Chlorogenic acid, a polyphenol, has demonstrated multiple mechanisms through which it exerts antidiabetic activity, including inhibition of alpha-glucosidase and the glucose-elevating liver enzyme glucose-6-phosphatase, oxidative stress modulation, insulin sensitization, and AMPK activation (Bassoli 2008
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Findings suggest that it may initiate signaling cascades involving PI3K and AMPK, pathways associated with nutrient regulation and energy use
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