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M., & Domenicotti, C
When Conventional Pain Treatment Fails If pain persists despite medications, injections, or physical therapy, it is often a sign that: Inflammation is being driven by systemic factors Tissue damage is not healing adequately The nervous system remains stuck in a pain-sensitive state Foundational supports like nutrition, sleep, and recovery are insufficient At this point, continuing to suppress symptoms without addressing root causes can prolong suffering rather than resolve it
DOI: 10.1523/JNEUROSCI.20-18-06920.2000
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