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Intraperitoneal (i.p.) injections of 6 mmol kg 1 BSO or 14 mg kg 1 iAs dissolved in a 0.9% saline solution or 0.9% saline solution alone were administered to mice
Given that there is currently no definite treatment for mitochondrial disease, symptomatic treatment is particularly critical for patients
Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions
Rather than targeting obesity through a single mechanism, this 3-way agonist addresses the complex hormonal and metabolic networks that regulate body weight, treating obesity as the multifaceted metabolic disease it truly is
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