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In human studies, hexarelin at approximately 1 to 2 mcg/kg IV produced plasma GH peaks that were among the highest of any synthetic secretagogue tested at that time, with Ghigo et al

Compared with the control group, study participants who supplemented with taurine had a significant improvement in the primary outcome of reducing risk of metabolic syndrome, demonstrated by the following weighted mean changes: systolic blood pressure - 4 mm Hg diastolic blood pressure -1.5 mm Hg triglycerides -18.3 mg/dL fasting blood glucose -5.9 mg/dL There were also significant improvements in secondary outcomes as shown by the following weighted mean changes: LDL cholesterol - 6.5 mg/dL total cholesterol - 8.3 mg/dL fasting insulin -1.52 IU/L HOMA-IR (calculation of insulin resistance) - 0.7 There was no significant effect on HDL, body weight, and BMI

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