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Moreover, in light of the growing evidence demonstrating the benefits of incretin-based therapies on both metabolic health and cardiovascular diseases, regulatory agencies such as the Food Drug Administration (FDA) and the European Medicines Agency (EMA) have approved their use for type 2 diabetes, reduction of cardiovascular risk and for chronic weight management in patients with morbid obesity [5,6,7,8]

As the feeding time increased, control mice accumulated much more hepatic fat, while GSTM2 overexpression suppressed hepatic fat accumulation (Fig

GLP-1 medications are typically initiated at low doses and increased slowly over several weeks or months, as per the product SmPC (Summary of Product Characteristics)