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The IRS1 and TRS1 genes from human cytomegalovirus (HCMV) have been inserted into HSV-2 to improve protein synthesis and replication by inhibiting PKR kinase activity and autophagy, thereby facilitating robust viral protein production and survival within tumor cells ( Table 1 Genetic modification of the modified oHSV
PT-141 works on the nervous system to enhance libido, improve arousal, and promote overall sexual satisfaction
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