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Clinical trials evaluating semaglutide have not identified bone loss as a significant adverse effect, though it should be noted that bone mineral density (BMD) was not specifically assessed in most studies
Most reported changes relate to energy, mood, weight loss, or confidence shifts during treatment rather than medication effects on sexual organs
Examples include Wegovy (injectable and pill), Ozempic, Zepbound, and Mounjaro
Potential interactions with concomitant medications Many semaglutide users with PCOS or metabolic syndrome also receive medications such as metformin or spironolactone
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