is toujeo a glp-1 Toujeo® U-300 (insulin glargine) injection 300 Units/mL Proven A1C Reduction | Toujeo®

& Maki, M

doi: 10.1089/neu.2013.3193

In the SURMOUNT-1 Phase 3 trial (N=2,539), Tirzepatide at 15mg produced 22.5% mean weight reduction over 72 weeks compared to 2.4% for placebo

employed in osteoarthritis and cartilage regeneration research Pigs Used for pharmacokinetic profiling and oral bioavailability studies Cynomolgus monkeys 9-month chronic toxicology studies via oral gavage Human subjects Approximately 900 participants across six clinical trials examining safety and efficacy Research Limitations & Regulatory Status Critical Gaps in Current Evidence Despite over 25 years of research and extensive clinical testing, AOD-9604 faces substantial evidence gaps that have prevented therapeutic development