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The FDA will continue to actively monitor for violations of federal law involving the marketing of GLP-1 products and will take appropriate enforcement action against the manufacture, distribution and sale of illegal drug products, spokesperson Emily G

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Gastrointestinal distension by ISF significantly reduced short-term food intake without aversive behavior, and this effect was significantly attenuated by pretreatment with GLP-1R antagonist or chemical ablation of vagal sensory neurons (Fig