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Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial

Benefits include increased energy, improved fat metabolism, healthier skin, stronger nails, better mood, enhanced digestion, and support for weight loss when paired with a healthy diet and exercise

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Initial assessment typically includes full blood count, serum B12, serum folate, and anti-intrinsic factor antibodies, with coeliac testing if indicated