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If a dose is missed, patients could apply it when remembered on the same day or resume the regular schedule at the next planned administration-double dosing is not recommended
Such binding may displace other regulatory proteins, making DNA more accessible for transcriptional machinery, potentially inducing neuronal cell differentiation in retinal and periodontal ligament stem cells (hPDLSCs)
Second, if the vial has been reconstituted for more than 3-4 weeks, peptide degradation may have reduced the effective concentration slightly, even with proper refrigeration
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