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According to the American College of Lifestyle Medicine (ACLM), there are six pillars of lifestyle, including a whole-food, plant-predominant eating pattern, physical activity (PA), stress management, positive social relationships, restorative sleep, and the avoidance of risky substances (59, 60) (Figure 3)

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Using singlenucleus RNA sequencing, the researchers found that H1 and H2 histamine receptors are enriched in excitatory neurons